An FDNY spokesperson said the crash happened just before 2 p.m. at Bronx River Parkway and East 223rd Street in Wakefield,
Eight people were injured in the crash, with one of them suffering injuries that could be life threatening, FDNY said.
Officials could not give a final number of cars involved, but said initial reports were 15 cars were involved, though it could have been as many as 20.
At least a dozen other crashes were reported in the tri-state area Saturday, as a winter storm brought snow to much of New York and New Jersey.
Snow showers began in the tri-state area Saturday afternoon and are expected to last through the evening.